Biomarkers for pancreatic cancer: is it ready for primetime?
نویسندگان
چکیده
Standard treatment for advanced pancreatic cancer has had minimal impact on natural course of the disease. Current standard chemotherapy for healthy, robust patients remains FOLFIRINOX (5fluorouracil, leucovorin, oxaliplatin, and irinotecan) chemotherapy which showed 4-month overall survival benefit compared to gemcitabine alone [2]. Recently MPACT study showed that adding nabpaclitaxel to gemcitabine significantly improved overall survival compared to gemcitabine (8.5 months vs. 6.7 months P=0.000015). However, the combination remains more toxic compared to gemcitabine [3].
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عنوان ژورنال:
- JOP : Journal of the pancreas
دوره 14 4 شماره
صفحات -
تاریخ انتشار 2013